The BeadBeater is a unique but simply designed apparatus. A solid Teflon® impeller rotating at high speed forces thousands of minute glass beads to collide in a specially shaped vessel. Cells are disrupted quickly, efficiently and safely. Being a totally sealed system, no air is introduced into the preparation - no irritating or toxic aerosols are formed. One can get better than 90% cell disruption in less than 3 minutes. The apparatus is easy to operate, requires no auxiliary supplies or equipment and is essentially maintenance free. The beads settle out in seconds and can be re-used.