RGD sequences are motifs on extracellular matrix proteins promoting adhesion to cellular integrin receptors. The 3-D Life RGD Peptide contains a RGD motif and a thiol group on the N-terminus. The thiol group is used to immobilize the peptide on thiol-reactive polymers in 3-D Life Hydrogels. The immobilized peptide promotes adhesion of cells carrying the appropriate integrin receptor.
For instructions, please consult General Protocols GP-1 “Preparation of 3-D Life Fast Gelling Hydrogels” or GP-2 “Preparation of 3-D Life Slow Gelling Hydrogels” and the 3-D Life Hydrogels User Guide on www.cellendes.com.