Easily generate publication-quality images at high throughput speeds
Whether you are performing assay development, compound screens, transfection assays or looking at a few samples in great detail, and whether you are using 3D models (such as spheroids, Organoids), Zebrafish imaging, primary cells, fixed cells or live cell imaging, WiScan® Hermes is the solution for you.
WiScan Hermes, IDEA Bio-Medical’s automated imaging system for high content screening (HCS) provides the unique combination of the two contradicting primary functions of automated microscopy: Image quality and acquisition speed.
WiScan® Hermes’ mechanisms are based on patents, creatively designed to meet heavy duty operation demands (24/7) with full process robustness.
WiScan® Hermes is a cost-effective system that is both sophisticated and flexible, offering 7 fluorescence colors, bright field option, and a large range of air objectives. The system can accommodate a variety of multi-well plates and sample formats (slides, dishes…) and offers environmental control for live cell assays.
It doesn’t matter if you are a beginner or an experienced microscopist, Hermes easily allows you to look deeper into your samples. The system is intuitively operated. Its built-in applications are extremely easy to use, and are operated at the push-of-a-button.
|3D reader||EPI-fluorescence inverted optics mounted on XYZ (patented) linear scanner|
|Auto Focus||Patented ultra-fast laser-based Auto Focus with 100nm resolution|
|XY motion||Accurate positioning with 200nm repeatability|
|Illumination sources||7 optional LED sources (DAPI,CFP,GFP,YFP,RFP,mCherry,CY5). Transmission: White LED source|
|Optical Filters||2 emission filters and compatible dichroic filters (automatically exchanged)|
|Objectives (Air)||Choice of air objectives in the range: 2X to 60X, high NA.|
|Camera||High sensitivity CCD camera with 1.3MPixel resolution|
|Sample format||Supports full-area screening of 6-1536 well plates Supports slides, microarrays, 35 mm dish formats. U-shaped bottom plats are optional.|
|Computer||PC with Windows® operating system and touch screen.|
|Enclosure||Allows operation in fully lit areas|
|Desktop standalone platform||47 W x 72 D x 57 H (cm), 18.5 W x 28.5 D x 22.4 H (inches) With plate cover closed|
Live Cell Imaging Module:
|Live cell imaging||Allow long time lapse experiments. Sample does not move during most of the scanning process.|
|Live cell conditions||
Object Mapping (Rare Event Detection) Module:
|Object mapping for rare events detection||
|Analysis tools||WiSoft® based image processing tools for object definition and detection in the first low magnification scan and further tools to analyze the detected objects with high magnification|
|Objectives||Automatic objective exchanger of up to 3 objectives at a time|
|Throughput||Enhances the throughput of high magnification scanning of rare objects|
|Statistical tools||Provides automatic decision resulting in efficient screening for minimum required objects in a well|
High Throughput (enhanced acquisition speed) Module:
|Combination of HCS and HTS||Ultra-fast High Content Screening unit|
|Image acquisition speed||>10 images per second (depends on experiment conditions)|
|Throughput||A full 96-well plate screening using 10X magnification with a single field per well, three color fluorescence, 150 ms total exposure time per field, runs in ~2 minutes. With some applications, this will include data processing and analysis results simultaneously with image acquisition.|
Automation Module (interfacing to external robotic arms):
|Remote accessibility||Protocols ( applications and screening parameters ) execution and management|
|External loader compatibility (Robot/manipulator)||
|External loader(Robot/manipulator) integration||Full integration support|